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复合型药片可降低血压和胆固醇
A Combination Pill Lowers Blood Pressure and Bad Cholesterol
复合型药片可降低血压和胆固醇
Studies have shown that the fewer medicines a person has to take the more likely he or she will take them. Last week, a study was released about a new treatment that combines five medicines for heart disease in one pill. Salim Yusuf of McMaster University in Hamilton, Ontario, Canada was the lead investigator. He presented the findings at the American College of Cardiology Conference in Orlando, Florida.
The experimental drug is known as Polycap. It contains aspirin, a drug to lower cholesterol and three medicines to lower blood pressure. The study was carried out at fifty health centers across India. More than two thousand people between the ages of forty-five and eighty took part in the study. All had at least one risk factor for heart disease. These include high blood pressure, high cholesterol, diabetes or being severely overweight.
The people were divided into nine groups of about two hundred people each. One group took Polycap. The other groups took either a single drug or different combinations of the medicines in the Polycap pill. The study showed that Polycap lowered blood pressure and cholesterol without many side effects. Doctor Yusuf said the single pill, taken once a day, could reduce the average person's risk of heart disease and stroke by about half. The maker of Polycap, Cadila Pharmaceuticals of India, paid for the study.
Cardiovascular diseases of the heart and blood vessels are the number one cause of death around the world. These diseases kill more than seventeen million people every year.
Eighty percent of them are in low and middle income countries. Doctor Yusuf said the single pill treatment could revolutionize heart disease prevention. People would be more likely to take one pill a day than many pills. And one pill would cost less than several pills.
Other heart doctors say heart disease prevention is important but not necessarily with pills. They say patients might be able to get the same results with changes in diet and exercise.
Doctors say that more research on Polycap is needed. They say the drug should be tested on thousands more people, including those in different risk, age and ethnic groups.
研究表明，一个人服用的药物越少，他就越有可能服用药物。上周发布了一项关于治疗方法的新成果——将治疗心脏病的五种药物置于一片药中。Salim Yusuf 是麦克马斯特大学(位于加拿大安大略省汉密尔顿市)的首席调查员。他在佛罗里达，奥兰多市举行的美国心脏病学院年会上展示了自己的研究成果。
这个实验药物就是Polycap。该药物含有阿司匹林，一种降低胆固醇的药物和三种降低血压的药物。这项研究是在印度50个健康中心进行的。两千多个年龄在45岁到80岁的人参加了这项研究。所有受试者至少有一个患心脏病的风险因素，比如高血压，高胆固醇，糖尿病或严重超重。
受试者被分成九组，每组大约两百人。其中一组服用Polycap，其他组有的单服一种药物，有的服用Polycap成分经不同搭配形成的药物。研究结果表明，Polycap可降低血压和胆固醇，而不会有过多副作用。Yusuf 博士说，每天服用一药片可以把普通人患心脏病和中风的风险减少一半。Polycap的制造者，印度Cadila 制药公司资助了这项研究。
心血管疾病是全世界致人死亡的头号病因。每年有一千五百万人死于这类疾病。其中80%的人集中在中低收入国家。
博士Yusuf说，只需服用一片药的治疗方法，将会为心脏病的预防带来一场革命。比起服用多片药，人们更倾向于服用单片药，并且单片药比多片药花费更少。
其他的心脏科医生认为，心脏病的预防很重要，但不一定要用药物。他们说，病人通过改变饮食和加强锻炼也能得到相同的结果。
医生们说，对于Polycap还需要更多的研究，并且还需要在上千人身上测试，受试者包括那些处于不同风险期，年龄段和民族的人。
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